Dr. Lara Stevanato
Dr. Arianna Hustler
ANGLE is a UK and US based medical diagnostics company. ANGLE has developed the Parsortix CTC capture and harvest system for the enrichment of circulating tumor cells from blood. The system captures CTCs on the basis of their larger size and lower compressibility than other blood components. This approach avoids a bias that can be introduced when cells are captured on the basis of antigen expression. Importantly, the system can deliver highly enriched and viable CTCs in solution, ready to be used for a range of downstream molecular and functional analysis.
ANGLE has initiated two 200 patient clinical studies in Europe and the US for the Company’s first clinical application for detection of ovarian cancer in women with a high risk pelvic mass. Furthermore, following successful pilot studies, ANGLE is assessing the potential to develop additional clinical applications in metastatic breast cancer and prostate cancer.