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Selected publications of CANCER-ID Partners

Methods to determine limit of detection and limit of quantification in quantitative real-time PCR (qPCR)

Biomolecular Detection and Quantification, April 2017

Authors: Forootan A, Sjoeback R, Bjoerkman J, Sjoegreen B, Linz L, Kubista M

 

Integrating liquid biopsies into the management of cancer

Nature Reviews, March 2017

Authors: Siravegna G, Marsoni S, Siena S, Bardelli A

 

Improving the CellSearch® system

Expert Review of Molecular Diagnostics, October 2016

Authors: Swennenhuis JF, van Dalum G, Zeune LL, Terstappen LWMM

 

Zirkulierende Tumorzellen: Ist die Metastasierung bald vorhersagbar?

Perspektiven der Onkologie, September 2016

Authors: Gorges TM and Pantel K

 

Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells

Cancer Diagnostics, September 2016

Authors: Gorges TM, Kuske A, Röck K, Mauermann O, Müller V, Peine S, Verpoort K, Novosadova V, Kubista M, Riethdorf S, Pantel K

 

Inferring expressed genes by whole-genome sequencing of plasma DNA

Nature Genetics, August 2016

Authors: Peter Ulz et al.

 

Capture of Tumor cells on Anti-EpCam-funcionalized Poly (acrylic acid)-coated surfaces

ACS Appl Mater Interfaces, August 2016

Authors: Andrée KC, Barradas AMC, Nguyen AT, Mentink A, Stojanovic I, Baggerman J, van Dalum J, van Rijn CJM, and Terstappen LWMM

 

Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer

Mol Oncol., July 2016

Authors: Gasch C, Oldopp T, Mauermann O,Gorges TM, Andreas A, Coith C, Mueller V, Fehm T, Janni W, Pantel K, Riehtdorf S

 

Characterization of different subpopulations in non-small cell lung cancer

Sci Rep., June 2016

Authors: Hanssen et al.

 

Improved dectection of circulating tumor cells in metastatic colorectal cancer by the combination of the CellSearch® System and the AdnaTest®

PLOS ONE, May 2016

Authors: Gorges TM, Stein A, Quidde J, Hauch S, Röck K, Riehtdorf S, Joosse S, Pantel K

 

Multiscale Segmentation via Bregman Distances and Nonlinear Spectral Analysis

Mol Oncol, April 2016

Authors: Zeune L, van Dalum G, Terstappen LWMM, van Gils SA, Brune C


Challenges in circulating tumor cell detection by the CellSearch System

Mol Oncol, March 2016

Authors: Andree KC, van Dalum G, Terstappen LW.

 

Blood circulation tumor DNA for non-invasive genotyping of colon cancer patients

Molecular Oncology, December 2015

Authors: Siravegna G, Bardelli A

 

Heterogeneous PSMA expression on circulating tumor cells - a potential basis for stratification and monitoring of PSMA-directed therpies on prostate cancer

Oncotarget, April 2016

Authors: Gorges TM, Riethdorf S, von AHsen O, Nastaly P, Röck K, Boede M, Peine S, Kuske A, Schmid E, Kneip C, König F, Rudolph M, Pantel K

 

Intraindividual Temporal miRNA Variability in Serum, Plasma, and White Blood Cell Subpopulations

Biopreserv Biobank, April 2016

Authors: Ammerlaan W, Betsou F

 

MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations

Science Translational Medicine, February 2016

Authors: Arena S, Siravegna G, Mussolin B, Kearns JD, Wolf B, Misale S, Lazzari L, Bertotti A, Trusolino L, Adjei A, Montagut C, Nicolantonio F, Nering R, Bardelli A

 

Potential of circulating tumor cells as blood-based biomarkers in cancer liquid-biopsy

 

Pharmacogenomics, January 2016

Authors: Schlange T and Pantel K

 

Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells.

 

Clin Cancer Res., December 2015

Authors: Gorges TM, Penkalla N, Schalk T, Joosse S, Riethdorf S, Tucholski J, Lucke K, Wikman H, Jackson SM, Brychter N, von Ahsen O, Schumann C, Krahn T, Pantel K. 

 

A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells.

 

Int J Cancer, January 2016

Authors: Hvichia GE, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves RP, Stoecklein NH, Wikman H, Riethdorf S, Pantel K, Gorges TM

 

Clinical evaluation of a novel microfluidic device for epitope-independent enrichment of circulating tumour cells in patients with small cell lung cancer.

 

Analyst, January 2016

Authors: Chudziak J, Burt DJ, Mohan S, Rothwell DG, Mesquita B, Antonello J, Dalby S, Ayub M, Priest L, Carter L, Krebs MG, Blackhall F, Dive C, Brady G.

 

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution

 

Expert Review of Molecular Diagnostics, December 2015

Authors: Stoecklein N, Fischer J, Niederacher D, Terstappem LWMM

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample.

 

Molecular Oncology, November 2015

Authors:Rothwell DG, Smith N, Morris D, Leong HS, Li Y, Hollebecque A, Ayub M, Carter L, Antonello J, Franklin L, Miller C, Blackhall F, Dive C, Brady G.

 

Industry-academia collaborations for biomarkers

 

Nature Reviews, October 2015

Authors: Khusru Asadullah, Andreas Busch, Matthias Gottwald, Petra Teinke and Lilla Landeck

Characterization of DNA Methylation in Circulating Tumor Cells

 

genes, October 2015

Authors: Constantin F. Pixberg, Wolfgang A. Schulz, Nikolas H. Stoecklein and Rui P. L. Neves

 

Data Normalization Strategies for MicroRNA Quantification

 

Clin Chem, September 2015

Authors: H. Schwarzenbach, A. Machado da Silva, G. Calin and K. Pantel

 

CCR 20th Anniversary Commentary: Paving the Way for Circulating Tumor Cells

 

Clin Cancer Res, June 2015

Authors: W. Jeffrey Allard and Leon W.M.M. Terstappen

 

The Biology of Circulating Tumor Cells

 

Oncogene, June 2015

Authors: K. Pantel and M. Speicher

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