The Analysis of Circulating Tumour Cells (ACTC) Lab, University of Athens, Greece (http://en.actc-lab.chem.uoa.gr/) is focused on CTC analysis during the last 15 years. Our group is specializing on the development, analytical validation and clinical evaluation of molecular assays for the detection, enumeration and molecular characterization of CTCs.

Our main research interests are on:

• Development of Companion Diagnostic assays in the field of Liquid biopsy
• Development of singleplex and multiplex quantitative RT-qPCR assays for the detection and molecular characterization of CTCs
• Development and clinical evaluation of multiplex assays for gene expression in CTCs based on the liquid bead array (Luminex system)
• Development and clinical evaluation of DNA methylation assays in CTCs and ctDNA
• Development and clinical evaluation of highly sensitive assays for mutation analysis in CTCs and in ctDNA
• Evaluation of circulating miRNAs as tumor biomarkers in plasma